Oral administration of fisetin promotes the induction of hippocampal long-term potentiation in vivo
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Block of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation
The effect of endogenous serotonin on long-term potentiation (LTP) in region CAI was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly en-hanced long-term potentiation of the CAI population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CAI...
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15 صفحه اولP3: Mechanisms of TrkB-Mediated Hippocampal Long-Term Potentiation in Learning and Memory
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متن کاملThe induction of long-term potentiation at amygdalo-hippocampal synapses in vivo.
Electrical stimulation of the basolateral amygdala (BLA) evoked synaptic potentials in the dentate gyrus (DG) of the hippocampus in anesthetized rats. To determine if this pathway possesses synaptic plasticity, we investigated the impact of several conditions of high-frequency stimulation on BLA-DG synaptic potentials in these rats. Application of two trains of 100-pulse, 100-Hz stimulation or ...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2018
ISSN: 1347-8613
DOI: 10.1016/j.jphs.2017.12.008